氘代间二溴苯合成
Published:
氘代间二溴苯的两条合成路线比较——H/D交换法与从氘代苯出发的多步合成法。
Posts by Collection
portfolio
posts_zh
注射死刑的翻车史
Published:
从三药组合到戊巴比妥单药方案，从欧洲断供到田纳西州翻车——”最人道的死刑”为何屡屡变成一场荒诞闹剧。
维生素B₆
Published:
维生素B₆的三种形式及其在氨基酸代谢中的关键作用——磷酸吡哆醛（PLP）的转氨、脱羧与消旋催化机制。
身高与数学常数
Published:
人的理想身高——男子约1.77米、女子约1.65米——恰好分别是圆周率π和自然常数e的平方根。
publications
Tellurium-zinc exchange between organotelluronium salts and diethylzinc-reaction of the in situ generated mixed diorganozinc with carbonyl compounds
Published in Tetrahedron Letters, 1998
Recommended citation: Wen-Hua Huang, Yao-Zeng Huang and Li-Xin Dai. "Tellurium-zinc exchange between organotelluronium salts and diethylzinc-reaction of the in situ generated mixed diorganozinc with carbonyl compounds." Tetrahedron Letters. 1998, 39, 6953-6956.
Download Paper
Improved synthesis of two silicon-containing aromatic dianhydrides
Published in Huaxue Shiji (Chemical Reagents), 1998
Recommended citation: 改良法合成两个含硅芳香二酸酐。黄文华，潘光明。化学试剂，1998，20，54-55.
Dynamics of alkene radical cation/phosphate anion pair formation from nucleotide C4’ radicals. The DNA/RNA paradox revisited
Published in Journal of the American Chemical Society, 2001
Recommended citation: David Crich and Wenhua Huang. "Dynamics of alkene radical cation/phosphate anion pair formation from nucleotide C4' radicals. The DNA/RNA paradox revisited." Journal of the American Chemical Society. 2001, 123, 9239-9245.
Download Paper
Synthesis of 30-40 mers of RNAs from unblocked monomers. A simple approach to the RNA world
Published in Chemical Communications, 2003
Recommended citation: Wenhua Huang and James P. Ferris. "Synthesis of 30-40 mers of RNAs from unblocked monomers. A simple approach to the RNA world." Chemical Communications. 2003, 1458-1459.
Download Paper
Catalysis in prebiotic chemistry: application to RNA synthesis
Published in Advances in Space Research, 2004
Recommended citation: James P. Ferris, Prakash C. Joshi, Kong-Jiang Wang, Shin Miyakawa and Wenhua Huang. "Catalysis in prebiotic chemistry: application to RNA synthesis." Advances in Space Research. 2004, 33, 100-105.
Download Paper
Oligonucleotides from montmorillonite catalysis; Analysis and modeling
Published in Origins of Life and Evolution of the Biosphere, 2006
Recommended citation: Michael F. Aldersley, James P. Ferris, Wenhua Huang, Prakash C. Joshi and Dmitri Zagorevski. "Oligonucleotides from montmorillonite catalysis; Analysis and modeling." Origins of Life and Evolution of the Biosphere. 2006, 36, 289-291.
One-step, regioselective synthesis of up to 50-mers of RNA oligomers by montmorillonite catalysis
Published in Journal of the American Chemical Society, 2006
Recommended citation: Wenhua Huang and James P. Ferris. "One-step, regioselective synthesis of up to 50-mers of RNA oligomers by montmorillonite catalysis." Journal of the American Chemical Society. 2006, 128, 8914-8919.
Download Paper
A facile synthesis of N-formylbenzamides by oxidative decarboxylation of N-aroylglycine induced by Ag+/S2O82-
Published in Journal of Chemical Research, 2006
Recommended citation: Wenhua Huang* and Li'e Zhang. "A facile synthesis of N-formylbenzamides by oxidative decarboxylation of N-aroylglycine induced by Ag+/S2O82-." Journal of Chemical Research. 2006, 738-739.
Download Paper
A facile synthesis of isoquinolines, beta-carbolines, and 3-deazapurines
Published in Synthetic Communications, 2007
Recommended citation: Wenhua Huang*, Jingyi Li and Lihua Ou. "A facile synthesis of isoquinolines, beta-carbolines, and 3-deazapurines." Synthetic Communications. 2007, 37, 2137-2143.
Download Paper
Conversion of N-acyl amino acids to imides via oxidative decarboxylation induced by Ag+/Cu2+/S2O82- in water
Published in Synthesis, 2008
Recommended citation: Wenhua Huang*, Meiling Wang and Hong Yue. "Conversion of N-acyl amino acids to imides via oxidative decarboxylation induced by Ag+/Cu2+/S2O82- in water." Synthesis. 2008, 1342-1344.
Download Paper
Novel route to N-acyl-N’-formyl aminal
Published in Synthetic Communications, 2009
Recommended citation: Hong Yue, Hongmei Zhang, Meiling Wang and Wenhua Huang*. "Novel route to N-acyl-N'-formyl aminal." Synthetic Communications. 2009, 39, 484-491.
Download Paper
One-pot synthesis of 2,4,5-trisubstituted oxazoles from N-acyl amino acids by a combination of cyclodehydration with N,N’-diisopropylcarbodiimide and Wittig olefination
Published in Tetrahedron, 2012
Recommended citation: Wenhua Huang*, Guangping Dong and Zumureti Mijiti. "One-pot synthesis of 2,4,5-trisubstituted oxazoles from N-acyl amino acids by a combination of cyclodehydration with N,N'-diisopropylcarbodiimide and Wittig olefination." Tetrahedron. 2012, 68, 977-981.
Download Paper
Synthesis of imides and benzoylureas by direct oxidation of N-methylenes of amides and benzylureas
Published in Journal of Chemical Research, 2013
Recommended citation: Wenhua Huang* and Mei-Li Xu. "Synthesis of imides and benzoylureas by direct oxidation of N-methylenes of amides and benzylureas." Journal of Chemical Research. 2013, 77-79.
Download Paper
Progress in direct amidation reactions catalyzed by boron compounds
Published in Huaxue yu Shengwu Gongcheng (Chemistry & Bioengineering), 2013
Recommended citation: 硼化合物催化的直接酰胺化反应研究进展。沙文彬，黄文华。化学与生物工程，2013，30（6），11-16.
One-pot synthesis of cyclopropane derivatives with a controlled cis:trans stereoselectivity by Wittig olefination-sulfur ylide cyclopropanation sequence
Published in Journal of Chemical Research, 2013
Recommended citation: Wenhua Huang* and Lai-Ling Wang. "One-pot synthesis of cyclopropane derivatives with a controlled cis:trans stereoselectivity by Wittig olefination-sulfur ylide cyclopropanation sequence." Journal of Chemical Research. 2013, 380-384.
Download Paper
Direct amide formation from N-arylglycine ethyl ester and carboxylic acids catalyzed by phenylboronic acid
Published in Journal of Chemical Research, 2013
Recommended citation: Wenhua Huang* and Wen-Bin Sha. "Direct amide formation from N-arylglycine ethyl ester and carboxylic acids catalyzed by phenylboronic acid." Journal of Chemical Research. 2013, 460-463.
Download Paper
N-(3-formylphenyl)glycine derivatives synthesis
Published in Huaxue Shiji (Chemical Reagents), 2013
Recommended citation: N-(3-甲酰基苯基)甘氨酸衍生物的合成。沙文彬，黄文华。化学试剂，2013，35（11），963-966.
Metal-free carbon-carbon cross-couplings between the ion pairs in sulfonium tetraphenylborates
Published in Tetrahedron Letters, 2014
Recommended citation: Mei-Li Xu and Wenhua Huang*. "Metal-free carbon-carbon cross-couplings between the ion pairs in sulfonium tetraphenylborates." Tetrahedron Letters. 2014, 55, 4230-4232.
Download Paper
Wittig olefination using phosphonium tetraphenylborate in the absence of additional base
Published in Phosphorus, Sulfur, and Silicon and the Related Elements, 2014
Recommended citation: Wenhua Huang*, Shuang-Hong Zhao and Guang-Ping Dong. "Wittig olefination using phosphonium tetraphenylborate in the absence of additional base." Phosphorus, Sulfur, and Silicon and the Related Elements. 2014, 189, 1802-1810.
Download Paper
Syntheses of 9-triptycylisothiocyanate, (10-amino-9-triptycyl)carboxylic acid and their derivatives
Published in Synthetic Communications, 2014
Recommended citation: Mei-Li Xu and Wenhua Huang*. "Syntheses of 9-triptycylisothiocyanate, (10-amino-9-triptycyl)carboxylic acid and their derivatives." Synthetic Communications. 2014, 44, 3435-3440.
Download Paper
Aryltriolborates as air- and water-stable bases for Wittig olefination
Published in Synthesis, 2015
Recommended citation: Wenhua Huang*, Shuang-Hong Zhao, and Ning Xu. "Aryltriolborates as air- and water-stable bases for Wittig olefination." Synthesis. 2015, 47, 359-366.
Download Paper
In situ generation of formaldehyde and triphenylphosphine from (hydroxymethyl)triphenylphosphonium and its application in Wittig olefination
Published in Synthetic Communications, 2015
Recommended citation: Wenhua Huang* and Jie Xu. "In situ generation of formaldehyde and triphenylphosphine from (hydroxymethyl)triphenylphosphonium and its application in Wittig olefination." Synthetic Communications. 2015, 45, 1777-1782.
Download Paper
Cyclic alpha-alkoxyphosphonium salts from (2-(diphenylphosphino)phenyl)methanol and aldehydes and their application in synthesis of vinyl ethers and ketones via Wittig olefination
Published in The Journal of Organic Chemistry, 2015
Recommended citation: Wenhua Huang*, Hong-Ying Rong, and Jie Xu. "Cyclic alpha-alkoxyphosphonium salts from (2-(diphenylphosphino)phenyl)methanol and aldehydes and their application in synthesis of vinyl ethers and ketones via Wittig olefination." The Journal of Organic Chemistry. 2015, 80, 6628-6638.
Download Paper
Synthesis of 1-substituted 2,6,7-trioxa-4-phospha-1-borabicyclo[2.2.2]octan-1-uide
Published in Synthetic Communications, 2016
Recommended citation: Wenhua Huang* and Ning Xu. "Synthesis of 1-substituted 2,6,7-trioxa-4-phospha-1-borabicyclo[2.2.2]octan-1-uide." Synthetic Communications. 2016, 46(14), 1182-1186.
Download Paper
Synthesis of pinacol acetals catalyzed by (2-carboxyphenyl)diphenylphosphonium bromide
Published in Synthetic Communications, 2017
Recommended citation: Wenhua Huang* and Ning Xu. "Synthesis of pinacol acetals catalyzed by (2-carboxyphenyl)diphenylphosphonium bromide." Synthetic Communications. 2017, 47(22), 2133-2138.
Download Paper
Metal-Free Synthesis of aryltriphenylphosphonium bromides by the reaction of triphenylphosphine with aryl bromides in refluxing phenol
Published in ACS Omega, 2019
Recommended citation: Wenhua Huang* and Chun-Hong Zhong. "Metal-Free Synthesis of aryltriphenylphosphonium bromides by the reaction of triphenylphosphine with aryl bromides in refluxing phenol." ACS Omega. 2019, 4(4), 6690-6696.
Download Paper
Synthesis of aryldiphenylphosphine oxides by quaternization of tertiary diphenylphosphines with aryl bromides followed by the Wittig Reaction
Published in ACS Omega, 2020
Recommended citation: Chun-Hong Zhong and Wenhua Huang*. "Synthesis of aryldiphenylphosphine oxides by quaternization of tertiary diphenylphosphines with aryl bromides followed by the Wittig Reaction." ACS Omega. 2020, 5(26), 16010-16020.
Download Paper
Synthesis of tertiary phosphine oxides by alkaline hydrolysis of quaternary phosphonium zwitterions using excess t-BuOK and stoichiometric water
Published in Synthetic Communications, 2021
Recommended citation: Chun-Hong Zhong and Wenhua Huang*. "Synthesis of tertiary phosphine oxides by alkaline hydrolysis of quaternary phosphonium zwitterions using excess t-BuOK and stoichiometric water." Synthetic Communications. 2021, 51(10), 1537-1546.
Download Paper
Transition metal-free domino aryl-aryl coupling/phospha-Michael addition of diarylphosphinite to alpha,beta-unsaturated ketones triggered by alkaline hydrolysis of (4-(2-alkenoyl)phenyl)triarylphosphonium salts
Published in Phosphorus, Sulfur, and Silicon and the Related Elements, 2022
Recommended citation: Wenhua Huang* and Jing-Yu Xue. "Transition metal-free domino aryl-aryl coupling/phospha-Michael addition of diarylphosphinite to alpha,beta-unsaturated ketones triggered by alkaline hydrolysis of (4-(2-alkenoyl)phenyl)triarylphosphonium salts." Phosphorus, Sulfur, and Silicon and the Related Elements. 2022, 197(2), 96-108.
Download Paper
Synthesis and Wittig olefination of (2-methyl-3-oxoisoindolin-1-yl)triphenylphosphonium tetrafluoroborate: facile access to 3-alkylidene-2-methylisoindolin-1-ones
Published in Phosphorus, Sulfur, and Silicon and the Related Elements, 2024
Recommended citation: Wenhua Huang* and Yan-Hong Wang. "Synthesis and Wittig olefination of (2-methyl-3-oxoisoindolin-1-yl)triphenylphosphonium tetrafluoroborate: facile access to 3-alkylidene-2-methylisoindolin-1-ones." Phosphorus, Sulfur, and Silicon and the Related Elements. 2024, 199(1), 82-89.
Download Paper
talks
Blood Group and Disease Associations
Published:
1. ABO Blood Group and Disease Associations
talks_zh
血型与疾病的关联
Published:
1. ABO 血型与疾病的关联
teaching
My Science Fiction Stories
Science Fiction, , 2026
I write science fiction stories (in Chinese) under the pen name 熊首丹山 (Xiong Shou Dan Shan), serialized on the Fanqie Novel (番茄小说) platform. Click a title below to read it on Fanqie Novel.
teaching_zh
我的科幻小说
Published:
我在番茄小说平台以笔名「熊首丹山」发表科幻小说。点击下方篇名，即可前往番茄小说阅读：